Mebendazole dosing is never one-size-fits-all — the dose for pinworm is a single 100mg tablet, while hookworm and whipworm require 100mg twice daily for 3 days, and cancer protocols use entirely different schedules. This complete 2026 USA dosage guide covers every indication with exact doses, the 100mg vs 500mg decision explained, the household treatment rule for pinworm, the food bioavailability secret that most patients never hear, drug interactions.