Fibromyalgia affects 4 million Americans and takes an average of 5 years to diagnose — partly because blood tests and X-rays are normal, and partly because it was historically dismissed as imaginary. This complete guide covers the real neuroscience behind fibromyalgia, how it is now diagnosed, and all treatment options including the three FDA-approved medicines: Pregabalin, Duloxetine, and Milnacipran.